scaffolds - 80 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NODE_1_length_4080732_cov_42.568346

Region	Type	From	To
Region 1.1	T1PKS	33,354	79,115
Region 1.2	NRPS	130,566	182,552
Region 1.3	T1PKS,indole	280,885	332,358
Region 1.4	NRPS	909,066	945,195
Region 1.5	terpene	1,000,642	1,021,803
Region 1.6	T3PKS	1,678,085	1,714,342
Region 1.7	T3PKS	2,413,252	2,454,465
Region 1.8	NRPS	2,666,528	2,703,553
Region 1.9	T1PKS	2,769,037	2,813,769
Region 1.10	NRPS	3,006,090	3,052,714
Region 1.11	NRPS	3,111,833	3,180,933

NODE_2_length_2846945_cov_41.963601

Region	Type	From	To
Region 2.1	NRPS-like	112,919	153,178
Region 2.2	NRPS-like	227,901	269,224
Region 2.3	NRPS	418,323	460,552
Region 2.4	NRPS	2,655,225	2,748,150

NODE_3_length_2247054_cov_42.239890

Region	Type	From	To
Region 3.1	T1PKS	9,559	57,121
Region 3.2	indole	348,417	369,643
Region 3.3	NRPS	552,697	606,452
Region 3.4	NRPS	666,448	787,404
Region 3.5	NRPS-like	1,056,888	1,101,694

NODE_4_length_1882820_cov_42.055632

Region	Type	From	To
Region 4.1	T1PKS,terpene	35,604	75,585
Region 4.2	terpene	303,475	325,393
Region 4.3	NRPS	399,649	449,510
Region 4.4	T1PKS	516,726	557,973
Region 4.5	T1PKS	565,072	599,880
Region 4.6	T1PKS	1,114,454	1,161,984
Region 4.7	NRPS	1,684,445	1,728,560

NODE_5_length_1791657_cov_41.891995

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	terpene	424,684	446,449
Region 5.2	T1PKS,NRPS	1,040,303	1,092,173

NODE_6_length_1665573_cov_42.156638

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	T1PKS,terpene	686,041	736,619

NODE_7_length_1486334_cov_42.539256

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	NRPS	485,425	529,113
Region 7.2	NRPS	1,291,886	1,340,908

NODE_8_length_1477758_cov_42.631400

Region	Type	From	To
Region 8.1	other,T1PKS	486	51,190
Region 8.2	T1PKS	432,894	479,199
Region 8.3	T1PKS	545,289	592,597

NODE_9_length_1477272_cov_42.443578

Region	Type	From	To
Region 9.1	T1PKS	251,412	296,168
Region 9.2	indole	1,073,419	1,096,301
Region 9.3	T1PKS	1,157,585	1,217,999

NODE_10_length_1451633_cov_42.171569

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	NRPS-like	286,859	330,592

NODE_11_length_1090659_cov_42.590956

Region	Type	From	To
Region 11.1	T1PKS,NRPS	268,193	320,570
Region 11.2	NRPS-like	349,586	391,173
Region 11.3	NRPS	444,177	490,362
Region 11.4	terpene	1,009,464	1,030,444

NODE_12_length_1085158_cov_42.430848

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	T1PKS	798,562	845,300
Region 12.2	T1PKS	963,883	1,009,356

NODE_13_length_1066851_cov_42.619387

Region	Type	From	To
Region 13.1	T1PKS	1,136	37,695
Region 13.2	T1PKS	225,893	273,023
Region 13.3	NRPS	807,950	915,464

NODE_14_length_1005724_cov_42.454487

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	T3PKS,T1PKS	273,508	323,215

NODE_15_length_941171_cov_42.844257

Region	Type	From	To
Region 15.1	T1PKS	186,383	233,042
Region 15.2	NRPS	273,382	335,316
Region 15.3	NRPS,T1PKS	596,798	720,108
Region 15.4	NRPS	822,101	890,124

NODE_19_length_791210_cov_42.638320

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	T1PKS,NRPS-like	46,338	93,909

NODE_20_length_754805_cov_42.550344

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	NRPS,T1PKS	656,674	709,141

NODE_22_length_697479_cov_42.070416

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	NRPS	356,440	400,894

NODE_26_length_643428_cov_41.885604

Region	Type	From	To	Most similar known cluster		Similarity
Region 26.1	terpene	590,414	611,472

NODE_30_length_574181_cov_42.457501

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	NRPS,T1PKS	2,746	69,115

NODE_31_length_548174_cov_42.595227

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	NRPS,T1PKS	427,869	480,568

NODE_33_length_436582_cov_42.267914

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	terpene	46,231	67,421

NODE_34_length_366628_cov_43.004755

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	T1PKS,NRPS	195,159	247,224
Region 34.2	NRPS-like	283,415	326,528

NODE_38_length_300474_cov_42.105034

Region	Type	From	To	Most similar known cluster		Similarity
Region 38.1	T1PKS	31,353	78,889

NODE_40_length_293996_cov_42.939711

Region	Type	From	To
Region 40.1	T1PKS	2,889	47,226
Region 40.2	NRPS	79,867	126,898
Region 40.3	T1PKS	166,909	215,968

NODE_44_length_206991_cov_41.867573

Region	Type	From	To	Most similar known cluster		Similarity
Region 44.1	T1PKS	34,633	82,338

NODE_46_length_192017_cov_42.184917

Region	Type	From	To	Most similar known cluster		Similarity
Region 46.1	terpene	50,941	73,308

NODE_48_length_126658_cov_42.504625

Region	Type	From	To	Most similar known cluster		Similarity
Region 48.1	NRPS,T1PKS	1	85,434

NODE_49_length_115311_cov_42.194838

Region	Type	From	To	Most similar known cluster		Similarity
Region 49.1	NRPS-like	19,790	62,639

NODE_52_length_101685_cov_42.543993

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	T1PKS	40,673	88,526

NODE_53_length_97316_cov_42.115900

Region	Type	From	To	Most similar known cluster		Similarity
Region 53.1	NRPS,T1PKS	4,882	56,785

NODE_58_length_55987_cov_40.959900

Region	Type	From	To	Most similar known cluster		Similarity
Region 58.1	T1PKS	13,977	55,987

NODE_75_length_37189_cov_41.313699

Region	Type	From	To	Most similar known cluster		Similarity
Region 75.1	NRPS	1	37,189

NODE_85_length_32612_cov_41.031351

Region	Type	From	To	Most similar known cluster		Similarity
Region 85.1	T1PKS	1	30,341

NODE_92_length_29195_cov_40.099869

Region	Type	From	To	Most similar known cluster		Similarity
Region 92.1	T1PKS	1	29,195

NODE_95_length_26577_cov_43.470302

Region	Type	From	To	Most similar known cluster		Similarity
Region 95.1	NRPS-like	1	26,577

NODE_113_length_19231_cov_41.530229

Region	Type	From	To	Most similar known cluster		Similarity
Region 113.1	T1PKS	1	19,231

NODE_164_length_9054_cov_53.570235

Region	Type	From	To	Most similar known cluster		Similarity
Region 164.1	terpene	1	9,054

NODE_281_length_2750_cov_54.194164

Region	Type	From	To	Most similar known cluster		Similarity
Region 281.1	terpene	1	2,750

Region	Type	From	To	Similarity
Region 1.1	T1PKS	33,354	79,115
Region 1.2	NRPS	130,566	182,552
Region 1.3	T1PKS,indole	280,885	332,358
Region 1.4	NRPS	909,066	945,195
Region 1.5	terpene	1,000,642	1,021,803
Region 1.6	T3PKS	1,678,085	1,714,342
Region 1.7	T3PKS	2,413,252	2,454,465
Region 1.8	NRPS	2,666,528	2,703,553
Region 1.9	T1PKS	2,769,037	2,813,769
Region 1.10	NRPS	3,006,090	3,052,714
Region 1.11	NRPS	3,111,833	3,180,933
Region 2.1	NRPS-like	112,919	153,178
Region 2.2	NRPS-like	227,901	269,224
Region 2.3	NRPS	418,323	460,552
Region 2.4	NRPS	2,655,225	2,748,150
Region 3.1	T1PKS	9,559	57,121
Region 3.2	indole	348,417	369,643
Region 3.3	NRPS	552,697	606,452
Region 3.4	NRPS	666,448	787,404
Region 3.5	NRPS-like	1,056,888	1,101,694
Region 4.1	T1PKS,terpene	35,604	75,585
Region 4.2	terpene	303,475	325,393
Region 4.3	NRPS	399,649	449,510
Region 4.4	T1PKS	516,726	557,973
Region 4.5	T1PKS	565,072	599,880
Region 4.6	T1PKS	1,114,454	1,161,984
Region 4.7	NRPS	1,684,445	1,728,560
Region 5.1	terpene	424,684	446,449
Region 5.2	T1PKS,NRPS	1,040,303	1,092,173
Region 6.1	T1PKS,terpene	686,041	736,619
Region 7.1	NRPS	485,425	529,113
Region 7.2	NRPS	1,291,886	1,340,908
Region 8.1	other,T1PKS	486	51,190
Region 8.2	T1PKS	432,894	479,199
Region 8.3	T1PKS	545,289	592,597
Region 9.1	T1PKS	251,412	296,168
Region 9.2	indole	1,073,419	1,096,301
Region 9.3	T1PKS	1,157,585	1,217,999
Region 10.1	NRPS-like	286,859	330,592
Region 11.1	T1PKS,NRPS	268,193	320,570
Region 11.2	NRPS-like	349,586	391,173
Region 11.3	NRPS	444,177	490,362
Region 11.4	terpene	1,009,464	1,030,444
Region 12.1	T1PKS	798,562	845,300
Region 12.2	T1PKS	963,883	1,009,356
Region 13.1	T1PKS	1,136	37,695
Region 13.2	T1PKS	225,893	273,023
Region 13.3	NRPS	807,950	915,464
Region 14.1	T3PKS,T1PKS	273,508	323,215
Region 15.1	T1PKS	186,383	233,042
Region 15.2	NRPS	273,382	335,316
Region 15.3	NRPS,T1PKS	596,798	720,108
Region 15.4	NRPS	822,101	890,124
Region 19.1	T1PKS,NRPS-like	46,338	93,909
Region 20.1	NRPS,T1PKS	656,674	709,141
Region 22.1	NRPS	356,440	400,894
Region 26.1	terpene	590,414	611,472
Region 30.1	NRPS,T1PKS	2,746	69,115
Region 31.1	NRPS,T1PKS	427,869	480,568
Region 33.1	terpene	46,231	67,421
Region 34.1	T1PKS,NRPS	195,159	247,224
Region 34.2	NRPS-like	283,415	326,528
Region 38.1	T1PKS	31,353	78,889
Region 40.1	T1PKS	2,889	47,226
Region 40.2	NRPS	79,867	126,898
Region 40.3	T1PKS	166,909	215,968
Region 44.1	T1PKS	34,633	82,338
Region 46.1	terpene	50,941	73,308
Region 48.1	NRPS,T1PKS	1	85,434
Region 49.1	NRPS-like	19,790	62,639
Region 52.1	T1PKS	40,673	88,526
Region 53.1	NRPS,T1PKS	4,882	56,785
Region 58.1	T1PKS	13,977	55,987
Region 75.1	NRPS	1	37,189
Region 85.1	T1PKS	1	30,341
Region 92.1	T1PKS	1	29,195
Region 95.1	NRPS-like	1	26,577
Region 113.1	T1PKS	1	19,231
Region 164.1	terpene	1	9,054
Region 281.1	terpene	1	2,750

No secondary metabolite regions were found in these records:: NODE_16_length_928553_cov_41.866648; NODE_17_length_830713_cov_42.136091; NODE_18_length_795796_cov_42.115771; NODE_21_length_731116_cov_42.497313; NODE_23_length_683514_cov_42.186118; NODE_24_length_654272_cov_41.995512; NODE_25_length_647181_cov_41.940438; NODE_27_length_611762_cov_42.088912; NODE_28_length_594880_cov_41.888925; NODE_29_length_583994_cov_41.979182; NODE_32_length_483603_cov_42.086748; NODE_35_length_345163_cov_42.607964; NODE_36_length_311594_cov_41.877512; NODE_37_length_308355_cov_41.646627; NODE_39_length_296462_cov_42.824603; NODE_41_length_260128_cov_41.410581; NODE_42_length_211500_cov_41.938815; NODE_43_length_211453_cov_41.871953; NODE_45_length_193493_cov_42.098151; NODE_47_length_172936_cov_42.864184; NODE_50_length_111505_cov_42.537010; NODE_51_length_109232_cov_43.235060; NODE_54_length_94486_cov_42.127477; NODE_55_length_71900_cov_42.979199; NODE_56_length_58883_cov_41.889620; NODE_57_length_56062_cov_41.748879; NODE_59_length_55022_cov_44.728092; NODE_60_length_53861_cov_46.390730; NODE_61_length_49554_cov_44.098268; NODE_62_length_48325_cov_40.780198; NODE_63_length_46557_cov_43.919170; NODE_64_length_45593_cov_59.629669; NODE_65_length_45425_cov_43.494730; NODE_66_length_45409_cov_45.751831; NODE_67_length_44961_cov_42.346515; NODE_68_length_42188_cov_43.366033; NODE_69_length_40853_cov_45.395600; NODE_70_length_40148_cov_131.992713; NODE_71_length_40116_cov_42.665077; NODE_72_length_39943_cov_130.106306; NODE_73_length_39100_cov_42.737949; NODE_74_length_37733_cov_41.044694; NODE_76_length_36822_cov_42.117104; NODE_77_length_36540_cov_132.462299; NODE_78_length_36252_cov_39.345100; NODE_79_length_36248_cov_45.916646; NODE_80_length_36087_cov_40.181783; NODE_81_length_35886_cov_45.675975; NODE_82_length_35494_cov_132.271254; NODE_83_length_34478_cov_41.940728; NODE_84_length_33728_cov_134.686161; NODE_86_length_32434_cov_43.714714; NODE_87_length_30535_cov_623.482041; NODE_88_length_30215_cov_43.074093; NODE_89_length_29368_cov_45.382882; NODE_90_length_29302_cov_41.152130; NODE_91_length_29264_cov_46.447117; NODE_93_length_27309_cov_48.992288; NODE_94_length_26741_cov_55.861911; NODE_96_length_26529_cov_41.448397; NODE_97_length_26046_cov_42.807732; NODE_98_length_25596_cov_44.277480; NODE_99_length_25506_cov_54.317747; NODE_100_length_24099_cov_46.248356; NODE_101_length_23786_cov_43.113543; NODE_102_length_23392_cov_50.156466; NODE_103_length_23299_cov_42.733141; NODE_104_length_23194_cov_42.454947; NODE_105_length_22339_cov_136.803746; NODE_106_length_22177_cov_45.511855; NODE_107_length_22034_cov_72.519197; NODE_108_length_21287_cov_51.633286; NODE_109_length_21282_cov_39.280123; NODE_110_length_20821_cov_46.424267; NODE_111_length_20325_cov_40.788226; NODE_112_length_19624_cov_44.009567; NODE_114_length_18799_cov_42.331962; NODE_115_length_18612_cov_43.883194; NODE_116_length_18183_cov_42.759085; NODE_117_length_18156_cov_51.569998; NODE_118_length_18127_cov_129.420831; NODE_119_length_17960_cov_126.856232; NODE_120_length_17795_cov_47.917372; NODE_121_length_16938_cov_43.280351; NODE_122_length_16836_cov_44.404380; NODE_123_length_16433_cov_42.200477; NODE_124_length_16322_cov_37.867467; NODE_125_length_16151_cov_264.159948; NODE_126_length_15678_cov_43.511890; NODE_127_length_15577_cov_36.692129; NODE_128_length_15290_cov_40.341156; NODE_129_length_15273_cov_50.688931; NODE_130_length_15120_cov_39.761816; NODE_131_length_15006_cov_52.348114; NODE_132_length_14842_cov_45.200271; NODE_133_length_14777_cov_44.987891; NODE_134_length_14577_cov_84.426897; NODE_135_length_14527_cov_34.484844; NODE_136_length_14226_cov_44.947699; NODE_137_length_13509_cov_47.349241; NODE_138_length_13398_cov_41.807447; NODE_139_length_13266_cov_134.192206; NODE_140_length_13071_cov_46.494536; NODE_141_length_13011_cov_44.932735; NODE_142_length_12995_cov_37.929169; NODE_143_length_12878_cov_987.672369; NODE_144_length_12593_cov_48.108102; NODE_145_length_12564_cov_41.786258; NODE_146_length_12336_cov_45.202708; NODE_147_length_12020_cov_37.333333; NODE_148_length_11994_cov_46.850466; NODE_149_length_11731_cov_37.107774; NODE_150_length_11649_cov_41.261753; NODE_151_length_11215_cov_130.846382; NODE_152_length_11003_cov_128.933370; NODE_153_length_10939_cov_49.474867; NODE_154_length_10823_cov_43.138842; NODE_155_length_10354_cov_48.945412; NODE_156_length_10305_cov_36.370356; NODE_157_length_9613_cov_50.314912; NODE_158_length_9563_cov_32.105524; NODE_159_length_9523_cov_49.113381; NODE_160_length_9394_cov_48.369754; NODE_161_length_9362_cov_174.439203; NODE_162_length_9128_cov_168.254558; NODE_163_length_9098_cov_42.819310; NODE_165_length_8996_cov_54.100796; NODE_166_length_8823_cov_40.564029; NODE_167_length_8756_cov_47.962899; NODE_168_length_8623_cov_251.565177; NODE_169_length_8592_cov_43.692308; NODE_170_length_8479_cov_50.192454; NODE_171_length_8461_cov_54.808325; NODE_172_length_8180_cov_46.761940; NODE_173_length_8051_cov_35.483948; NODE_174_length_7976_cov_53.111660; NODE_175_length_7891_cov_45.129895; NODE_176_length_7794_cov_45.338992; NODE_177_length_7747_cov_80.475228; NODE_178_length_7431_cov_84.821594; NODE_179_length_7390_cov_36.731164; NODE_180_length_7262_cov_54.719415; NODE_181_length_7151_cov_50.919423; NODE_182_length_7016_cov_48.686842; NODE_183_length_6911_cov_133.592479; NODE_184_length_6825_cov_64.018672; NODE_185_length_6712_cov_10175.061341; NODE_186_length_6671_cov_47.052775; NODE_187_length_6555_cov_59.958012; NODE_188_length_6455_cov_84.286767; NODE_189_length_6368_cov_45.972659; NODE_190_length_6354_cov_48.374064; NODE_191_length_6281_cov_46.257737; NODE_192_length_6256_cov_991.053083; NODE_193_length_6214_cov_31.475965; NODE_194_length_6148_cov_59.224510; NODE_195_length_6146_cov_50.569122; NODE_196_length_6119_cov_53.085568; NODE_197_length_6112_cov_47.951781; NODE_198_length_6101_cov_45.887284; NODE_199_length_6041_cov_38.953387; NODE_200_length_5997_cov_47.242736; NODE_201_length_5863_cov_51.269962; NODE_202_length_5824_cov_43.872803; NODE_203_length_5808_cov_176.374280; NODE_204_length_5786_cov_39.889823; NODE_205_length_5780_cov_44.600912; NODE_206_length_5703_cov_64.699609; NODE_207_length_5693_cov_47.351496; NODE_208_length_5676_cov_48.942847; NODE_209_length_5635_cov_35.371177; NODE_210_length_5632_cov_44.331953; NODE_211_length_5604_cov_57.720101; NODE_212_length_5570_cov_43.801384; NODE_213_length_5563_cov_28.843055; NODE_214_length_5517_cov_39.483272; NODE_215_length_5486_cov_54.288408; NODE_216_length_5450_cov_54.677834; NODE_217_length_5424_cov_45.670095; NODE_218_length_5413_cov_55.016117; NODE_219_length_5327_cov_14.783048; NODE_220_length_5249_cov_49.195476; NODE_221_length_5227_cov_136.868155; NODE_222_length_5160_cov_133.885501; NODE_223_length_5144_cov_38.215907; NODE_224_length_5140_cov_161.793008; NODE_225_length_5098_cov_64.846445; NODE_226_length_4999_cov_21.279358; NODE_227_length_4889_cov_20.002909; NODE_228_length_4850_cov_48.337733; NODE_229_length_4689_cov_49.829575; NODE_230_length_4659_cov_85.191619; NODE_231_length_4576_cov_62.993554; 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NODE_429_length_1034_cov_9.481714; NODE_430_length_1027_cov_39.147368; NODE_431_length_1020_cov_172.821845; NODE_432_length_1018_cov_161.356004; NODE_433_length_1013_cov_85.841880; NODE_434_length_1002_cov_18.884324

Compact view

NODE_1_length_4080732_cov_42.568346 - Region 1 - T1PKS

Download region GenBank file

Location: 33,354 - 79,115 nt. (total: 45,762 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 33353 - 79115:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-22

PKS_AT (924..1230): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; inactive: 54.2%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 66.5
inactive: 55.5
Methoxymalonyl-CoA: 38.6
Methylmalonyl-CoA: 35.3
Ethylmalonyl-CoA: 23.7
Propionyl-CoA: 21.2
Benzoyl-CoA: 21.1
fatty_acid: 16.6
Isobutyryl-CoA: 14.1
trans-1,2-CPDA: 13.8
2-Methylbutyryl-CoA: 13.7
CHC-CoA: 11.9
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

NODE_1_length_4080732_cov_42.568346 - Region 2 - NRPS

Download region GenBank file

Location: 130,566 - 182,552 nt. (total: 51,987 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 130565 - 182552:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-53

Search NORINE for peptide: strict or relaxed

AMP-binding (40..423): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvfelimihk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1075..1461): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvfsvagnik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2693..3091): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvldigaigk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_1_length_4080732_cov_42.568346 - Region 3 - T1PKS,indole

Download region GenBank file

Location: 280,885 - 332,358 nt. (total: 51,474 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 280884 - 332358:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 280884 - 320036:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-101

PKS_AT (954..1239): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 79.1
Methoxymalonyl-CoA: 60.8
Methylmalonyl-CoA: 53.4
inactive: 50.0
Ethylmalonyl-CoA: 37.1
Propionyl-CoA: 24.9
2-Methylbutyryl-CoA: 23.0
fatty_acid: 22.1
Benzoyl-CoA: 20.5
Isobutyryl-CoA: 20.1
CHC-CoA: 19.4
trans-1,2-CPDA: 14.8
Acetyl-CoA: 11.7
3-Methylbutyryl-CoA: 0.0

NODE_1_length_4080732_cov_42.568346 - Region 4 - NRPS

Download region GenBank file

Location: 909,066 - 945,195 nt. (total: 36,130 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 6, location 909065 - 945195:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-320

Search NORINE for peptide: strict or relaxed

AMP-binding (553..957): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawlvgffgk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_1_length_4080732_cov_42.568346 - Region 5 - terpene

Download region GenBank file

Location: 1,000,642 - 1,021,803 nt. (total: 21,162 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NODE_1_length_4080732_cov_42.568346 - Region 6 - T3PKS

Download region GenBank file

Location: 1,678,085 - 1,714,342 nt. (total: 36,258 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NODE_1_length_4080732_cov_42.568346 - Region 7 - T3PKS

Download region GenBank file

Location: 2,413,252 - 2,454,465 nt. (total: 41,214 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NODE_1_length_4080732_cov_42.568346 - Region 8 - NRPS

Download region GenBank file

Location: 2,666,528 - 2,703,553 nt. (total: 37,026 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NODE_1_length_4080732_cov_42.568346 - Region 9 - T1PKS

Download region GenBank file

Location: 2,769,037 - 2,813,769 nt. (total: 44,733 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NODE_1_length_4080732_cov_42.568346 - Region 10 - NRPS

Download region GenBank file

Location: 3,006,090 - 3,052,714 nt. (total: 46,625 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 12, location 3006089 - 3052714:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X - D-X - X - D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-1060

Search NORINE for peptide: strict or relaxed

AMP-binding (258..651): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvtlvgcvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1802..2199): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dnadagcvnk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2882..3279): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: damlvgavvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4421..4826): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: damlvgavik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5522..5922): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: digfvggifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_1_length_4080732_cov_42.568346 - Region 11 - NRPS

Download region GenBank file

Location: 3,111,833 - 3,180,933 nt. (total: 69,101 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 13, location 3111832 - 3180933:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X - ala - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-1092

Search NORINE for peptide: strict or relaxed

AMP-binding (36..436): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvyaisapmk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1119..1514): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: agifcgtgvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2194..2591): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: agmfcgtavk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3274..3673): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: damivcgvck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4368..4766): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: diwilgavik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5866..6264): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: agifcgtaik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-1094

Search NORINE for peptide: strict or relaxed

AMP-binding (114..561): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: emlvmggask
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_2_length_2846945_cov_41.963601 - Region 1 - NRPS-like

Download region GenBank file

Location: 112,919 - 153,178 nt. (total: 40,260 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 112918 - 153178:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-1452

Search NORINE for peptide: strict or relaxed

AMP-binding (13..417): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: nvwlwnvevk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_2_length_2846945_cov_41.963601 - Region 2 - NRPS-like

Download region GenBank file

Location: 227,901 - 269,224 nt. (total: 41,324 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 227900 - 269224:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-1510

Search NORINE for peptide: strict or relaxed

AMP-binding (40..364): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: nhcy--m--k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_2_length_2846945_cov_41.963601 - Region 3 - NRPS

Download region GenBank file

Location: 418,323 - 460,552 nt. (total: 42,230 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 418322 - 460552:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-1585

Search NORINE for peptide: strict or relaxed

AMP-binding (311..708): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dihdiaafsk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_2_length_2846945_cov_41.963601 - Region 4 - NRPS

Download region GenBank file

Location: 2,655,225 - 2,748,150 nt. (total: 92,926 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 2655224 - 2748150:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala - X - X - val - X - ile - X - X - X - X - X - X - ile - phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-2365

Search NORINE for peptide: strict or relaxed

AMP-binding (493..897): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dlwihcavik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1579..1978): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawmlgivfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2651..3054): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawmfsavyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4146..4547): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: dawflggtfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5220..5622): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawmfsvvyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6714..7115): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: dawflgvgyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7788..8189): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvwmfaavlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (9279..9678): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlwmtctvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (10359..10766): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawliggtmk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (11445..11848): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvwiytanlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (12933..13337): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawfygatfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (14012..14413): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dnwmlaavsk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (15077..15476): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: dgwfygasfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (16152..16553): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: dawtyaavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_3_length_2247054_cov_42.239890 - Region 1 - T1PKS

Download region GenBank file

Location: 9,559 - 57,121 nt. (total: 47,563 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 9558 - 57121:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-2401

PKS_AT (547..855): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 75.1
Methoxymalonyl-CoA: 70.0
Malonyl-CoA: 63.0
Isobutyryl-CoA: 42.6
Ethylmalonyl-CoA: 35.4
inactive: 30.3
Propionyl-CoA: 26.7
3-Methylbutyryl-CoA: 24.2
Benzoyl-CoA: 23.8
Acetyl-CoA: 16.0
CHC-CoA: 15.0
2-Methylbutyryl-CoA: 11.1
fatty_acid: 9.5
trans-1,2-CPDA: 7.9

NODE_3_length_2247054_cov_42.239890 - Region 2 - indole

Download region GenBank file

Location: 348,417 - 369,643 nt. (total: 21,227 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes

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Gene details

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NODE_3_length_2247054_cov_42.239890 - Region 3 - NRPS

Download region GenBank file

Location: 552,697 - 606,452 nt. (total: 53,756 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 552696 - 606452:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - D-X - X - pro - D-pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-2585

Search NORINE for peptide: strict or relaxed

AMP-binding (241..651): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvqfvgsick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1820..2210): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: shmivtsnvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3339..3735): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvedvgsifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4416..4812): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dimiyitlik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5507..5914): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dilivagvlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_3_length_2247054_cov_42.239890 - Region 4 - NRPS

Download region GenBank file

Location: 666,448 - 787,404 nt. (total: 120,957 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 666447 - 787404:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - leu - iva - iva - X - gln - X - iva) + (iva - X - iva - X - leu - X - gln - X - iva)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 666447 - 734861:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - leu - iva - iva - X - gln - X - iva)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 6, location 717269 - 787404:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (iva - X - iva - X - leu - X - gln - X - iva)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-2620

Search NORINE for peptide: strict or relaxed

AMP-binding (491..891): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dayavgvvik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1587..1987): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dfgcvgacik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2676..3076): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dafflgcvik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3769..4168): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4858..5266): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5964..6367): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dalligsvsk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7068..7466): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: dssiisaidk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (8170..8565): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dasivggifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (9257..9661): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgfvagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-2630

Search NORINE for peptide: strict or relaxed

AMP-binding (679..1083): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1767..2167): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlgiiggiik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2863..3264): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3957..4357): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dafaigvvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5049..5453): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dafflgcvik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6151..6554): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dalllgcvlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7246..7643): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: dgsivsaidk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (8336..8734): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: datlvgaimk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (9424..9826): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_3_length_2247054_cov_42.239890 - Region 5 - NRPS-like

Download region GenBank file

Location: 1,056,888 - 1,101,694 nt. (total: 44,807 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 7, location 1056887 - 1101694:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-2742

Search NORINE for peptide: strict or relaxed

AMP-binding (49..292): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: st-w---vpk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_4_length_1882820_cov_42.055632 - Region 1 - T1PKS,terpene

Download region GenBank file

Location: 35,604 - 75,585 nt. (total: 39,982 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 35603 - 75585:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-3190

PKS_AT (586..893): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 84.0
Methoxymalonyl-CoA: 66.1
Ethylmalonyl-CoA: 46.2
Propionyl-CoA: 44.7
Isobutyryl-CoA: 43.3
Malonyl-CoA: 31.2
Benzoyl-CoA: 23.9
trans-1,2-CPDA: 23.6
CHC-CoA: 23.1
fatty_acid: 22.6
3-Methylbutyryl-CoA: 20.3
2-Methylbutyryl-CoA: 18.4
inactive: 0.0
Acetyl-CoA: 0.0

NODE_4_length_1882820_cov_42.055632 - Region 2 - terpene

Download region GenBank file

Location: 303,475 - 325,393 nt. (total: 21,919 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

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NODE_4_length_1882820_cov_42.055632 - Region 3 - NRPS

Download region GenBank file

Location: 399,649 - 449,510 nt. (total: 49,862 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 399648 - 449510:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-ala - ala - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-3322

Search NORINE for peptide: strict or relaxed

AMP-binding (274..664): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: daffimavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1828..2237): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: pro
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dvslacsvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4058..4459): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dagdvaavek
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_4_length_1882820_cov_42.055632 - Region 4 - T1PKS

Download region GenBank file

Location: 516,726 - 557,973 nt. (total: 41,248 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NODE_4_length_1882820_cov_42.055632 - Region 5 - T1PKS

Download region GenBank file

Location: 565,072 - 599,880 nt. (total: 34,809 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 6, location 565071 - 599880:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-3381

PKS_AT (616..936): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Ethylmalonyl-CoA: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 63.3
Methoxymalonyl-CoA: 60.0
Propionyl-CoA: 41.5
Malonyl-CoA: 39.3
Ethylmalonyl-CoA: 30.2
Isobutyryl-CoA: 29.5
3-Methylbutyryl-CoA: 13.6
inactive: 12.0
trans-1,2-CPDA: 11.3
fatty_acid: 10.6
Benzoyl-CoA: 8.7
2-Methylbutyryl-CoA: 1.1
CHC-CoA: 0.0
Acetyl-CoA: -1.1

NODE_4_length_1882820_cov_42.055632 - Region 6 - T1PKS

Download region GenBank file

Location: 1,114,454 - 1,161,984 nt. (total: 47,531 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 7, location 1114453 - 1161984:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-3565

PKS_AT (550..845): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 62.5%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 70.2
Methylmalonyl-CoA: 65.6
Malonyl-CoA: 49.1
Ethylmalonyl-CoA: 35.6
Isobutyryl-CoA: 35.0
Propionyl-CoA: 26.9
Benzoyl-CoA: 21.2
Acetyl-CoA: 19.2
CHC-CoA: 19.1
2-Methylbutyryl-CoA: 19.0
3-Methylbutyryl-CoA: 10.8
trans-1,2-CPDA: 10.5
fatty_acid: 7.5
inactive: 0.0

NODE_4_length_1882820_cov_42.055632 - Region 7 - NRPS

Download region GenBank file

Location: 1,684,445 - 1,728,560 nt. (total: 44,116 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 8, location 1684444 - 1728560:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-3758

Search NORINE for peptide: strict or relaxed

AMP-binding (327..722): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvgmvgavyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_5_length_1791657_cov_41.891995 - Region 1 - terpene

Download region GenBank file

Location: 424,684 - 446,449 nt. (total: 21,766 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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Gene details

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NODE_5_length_1791657_cov_41.891995 - Region 2 - NRPS,T1PKS

Download region GenBank file

Location: 1,040,303 - 1,092,173 nt. (total: 51,871 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 1040302 - 1092173:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-4227

Search NORINE for peptide: strict or relaxed

PKS_AT (542..853): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 76.0
Methylmalonyl-CoA: 74.9
Malonyl-CoA: 69.7
Isobutyryl-CoA: 68.6
inactive: 40.9
Ethylmalonyl-CoA: 38.5
Propionyl-CoA: 30.4
2-Methylbutyryl-CoA: 29.8
Benzoyl-CoA: 21.7
trans-1,2-CPDA: 19.2
fatty_acid: 17.1
3-Methylbutyryl-CoA: 4.1
CHC-CoA: 2.9
Acetyl-CoA: 0.0

AMP-binding (2824..3252): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlvyyatvqk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_6_length_1665573_cov_42.156638 - Region 1 - T1PKS,terpene

Download region GenBank file

Location: 686,041 - 736,619 nt. (total: 50,579 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 686040 - 736619:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 686040 - 733287:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-4751

PKS_AT (535..850): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 78.5
Methoxymalonyl-CoA: 67.2
Isobutyryl-CoA: 31.2
inactive: 29.2
Propionyl-CoA: 28.7
Benzoyl-CoA: 18.7
trans-1,2-CPDA: 18.4
Malonyl-CoA: 15.7
Acetyl-CoA: 15.2
fatty_acid: 13.3
3-Methylbutyryl-CoA: 10.5
2-Methylbutyryl-CoA: 9.1
CHC-CoA: 8.7
Ethylmalonyl-CoA: 3.9

ETHZIMBMK001_gene-4759

Search NORINE for peptide: strict or relaxed

AMP-binding (28..265): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --lhiasptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-4760

Search NORINE for peptide: strict or relaxed

AMP-binding (53..227): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dn--mr---k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_7_length_1486334_cov_42.539256 - Region 1 - NRPS

Download region GenBank file

Location: 485,425 - 529,113 nt. (total: 43,689 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 485424 - 529113:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-5275

Search NORINE for peptide: strict or relaxed

AMP-binding (1323..1705): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: divycralgk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_7_length_1486334_cov_42.539256 - Region 2 - NRPS

Download region GenBank file

Location: 1,291,886 - 1,340,908 nt. (total: 49,023 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 1291885 - 1340908:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-5554

Search NORINE for peptide: strict or relaxed

AMP-binding (51..460): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gllhiasptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-5555

Search NORINE for peptide: strict or relaxed

AMP-binding (180..581): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvdhggavgk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_8_length_1477758_cov_42.631400 - Region 1 - T1PKS,other

Download region GenBank file

Location: 486 - 51,190 nt. (total: 50,705 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 485 - 51190:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 12572 - 51190:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-5614

PKS_AT (331..622): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 80.9
Methoxymalonyl-CoA: 47.6
Methylmalonyl-CoA: 45.1
inactive: 34.9
fatty_acid: 24.1
Isobutyryl-CoA: 21.1
Propionyl-CoA: 19.1
CHC-CoA: 13.9
Acetyl-CoA: 13.4
2-Methylbutyryl-CoA: 12.4
trans-1,2-CPDA: 12.0
Ethylmalonyl-CoA: 10.4
3-Methylbutyryl-CoA: 10.2
Benzoyl-CoA: 9.1

NODE_8_length_1477758_cov_42.631400 - Region 2 - T1PKS

Download region GenBank file

Location: 432,894 - 479,199 nt. (total: 46,306 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NODE_8_length_1477758_cov_42.631400 - Region 3 - T1PKS

Download region GenBank file

Location: 545,289 - 592,597 nt. (total: 47,309 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 5, location 545288 - 592597:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-5807

PKS_AT (372..685): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Ethylmalonyl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 83.6
Methoxymalonyl-CoA: 81.7
Ethylmalonyl-CoA: 61.7
Propionyl-CoA: 57.0
Malonyl-CoA: 57.0
Isobutyryl-CoA: 46.7
2-Methylbutyryl-CoA: 41.1
trans-1,2-CPDA: 31.7
fatty_acid: 18.9
CHC-CoA: 16.6
Benzoyl-CoA: 7.4
3-Methylbutyryl-CoA: 7.2
inactive: 0.0
Acetyl-CoA: 0.0

NODE_9_length_1477272_cov_42.443578 - Region 1 - T1PKS

Download region GenBank file

Location: 251,412 - 296,168 nt. (total: 44,757 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 251411 - 296168:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-6220

PKS_AT (535..839): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; Isobutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 83.5
Methoxymalonyl-CoA: 71.0
Malonyl-CoA: 55.0
Isobutyryl-CoA: 46.5
Ethylmalonyl-CoA: 46.3
Propionyl-CoA: 37.6
fatty_acid: 31.3
trans-1,2-CPDA: 30.1
Benzoyl-CoA: 25.2
CHC-CoA: 11.1
2-Methylbutyryl-CoA: 5.4
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ETHZIMBMK001_gene-6221

Search NORINE for peptide: strict or relaxed

AMP-binding (52..468): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: altwvggvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_9_length_1477272_cov_42.443578 - Region 2 - indole

Download region GenBank file

Location: 1,073,419 - 1,096,301 nt. (total: 22,883 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

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NODE_9_length_1477272_cov_42.443578 - Region 3 - T1PKS

Download region GenBank file

Location: 1,157,585 - 1,217,999 nt. (total: 60,415 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS products

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Predicted core structure(s)

For candidate cluster 3, location 1157584 - 1217999:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-6528

PKS_AT (512..836): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; 2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 76.8
Methoxymalonyl-CoA: 76.8
Malonyl-CoA: 73.8
Isobutyryl-CoA: 51.4
Propionyl-CoA: 37.4
fatty_acid: 36.9
3-Methylbutyryl-CoA: 34.9
Ethylmalonyl-CoA: 21.7
trans-1,2-CPDA: 21.2
Benzoyl-CoA: 18.7
inactive: 17.3
CHC-CoA: 10.4
2-Methylbutyryl-CoA: 5.2
Acetyl-CoA: 0.0

ETHZIMBMK001_gene-6531

PKS_AT (457..774): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 75.0%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 88.3
Methoxymalonyl-CoA: 71.3
Ethylmalonyl-CoA: 54.3
Malonyl-CoA: 46.9
Benzoyl-CoA: 30.4
Propionyl-CoA: 27.2
trans-1,2-CPDA: 25.1
Isobutyryl-CoA: 22.5
Acetyl-CoA: 21.5
fatty_acid: 20.2
CHC-CoA: 19.6
2-Methylbutyryl-CoA: 13.0
3-Methylbutyryl-CoA: 7.8
inactive: 0.0

NODE_10_length_1451633_cov_42.171569 - Region 1 - NRPS-like

Download region GenBank file

Location: 286,859 - 330,592 nt. (total: 43,734 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

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Predicted core structure(s)

For candidate cluster 1, location 286858 - 330592:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-6734

Search NORINE for peptide: strict or relaxed

AMP-binding (28..501): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dprhfvlrak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_11_length_1090659_cov_42.590956 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 268,193 - 320,570 nt. (total: 52,378 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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NRPS/PKS domains

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Predicted core structure(s)

For candidate cluster 1, location 268192 - 320570:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-7240

Search NORINE for peptide: strict or relaxed

PKS_AT (544..861): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 89.0
Ethylmalonyl-CoA: 72.6
Methoxymalonyl-CoA: 72.0
Malonyl-CoA: 60.8
Isobutyryl-CoA: 48.6
trans-1,2-CPDA: 36.4
Benzoyl-CoA: 36.3
Propionyl-CoA: 32.4
2-Methylbutyryl-CoA: 25.9
fatty_acid: 24.9
Acetyl-CoA: 15.6
inactive: 14.9
3-Methylbutyryl-CoA: 14.9
CHC-CoA: 9.5

AMP-binding (3056..3471): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: davqwgsisk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_11_length_1090659_cov_42.590956 - Region 2 - NRPS-like

Download region GenBank file

Location: 349,586 - 391,173 nt. (total: 41,588 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 2, location 349585 - 391173:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-7267

Search NORINE for peptide: strict or relaxed

AMP-binding (44..362): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --plvgvtlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_11_length_1090659_cov_42.590956 - Region 3 - NRPS

Download region GenBank file

Location: 444,177 - 490,362 nt. (total: 46,186 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

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Predicted core structure(s)

For candidate cluster 3, location 444176 - 490362:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-7302

Search NORINE for peptide: strict or relaxed

AMP-binding (588..980): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: davlvgavck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1664..2056): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlcflagclk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_11_length_1090659_cov_42.590956 - Region 4 - terpene

Download region GenBank file

Location: 1,009,464 - 1,030,444 nt. (total: 20,981 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NODE_12_length_1085158_cov_42.430848 - Region 1 - T1PKS

Download region GenBank file

Location: 798,562 - 845,300 nt. (total: 46,739 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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Predicted core structure(s)

For candidate cluster 1, location 798561 - 845300:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-7788

PKS_AT (532..850): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 81.0
Methylmalonyl-CoA: 76.7
Malonyl-CoA: 72.0
Ethylmalonyl-CoA: 48.1
Propionyl-CoA: 44.2
Isobutyryl-CoA: 37.5
2-Methylbutyryl-CoA: 32.4
trans-1,2-CPDA: 31.0
3-Methylbutyryl-CoA: 30.5
fatty_acid: 21.7
inactive: 21.2
Benzoyl-CoA: 21.2
Acetyl-CoA: 21.2
CHC-CoA: 14.6

NODE_12_length_1085158_cov_42.430848 - Region 2 - T1PKS

Download region GenBank file

Location: 963,883 - 1,009,356 nt. (total: 45,474 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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Predicted core structure(s)

For candidate cluster 2, location 963882 - 1009356:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-7841

PKS_AT (938..1236): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 75.8
inactive: 48.6
Methylmalonyl-CoA: 46.2
Methoxymalonyl-CoA: 38.6
Propionyl-CoA: 30.2
2-Methylbutyryl-CoA: 19.6
CHC-CoA: 13.7
Ethylmalonyl-CoA: 12.9
Benzoyl-CoA: 12.4
Isobutyryl-CoA: 12.1
Acetyl-CoA: 10.7
fatty_acid: 10.5
3-Methylbutyryl-CoA: 8.7
trans-1,2-CPDA: 0.0

NODE_13_length_1066851_cov_42.619387 - Region 1 - T1PKS

Download region GenBank file

Location: 1,136 - 37,695 nt. (total: 36,560 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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Predicted core structure(s)

For candidate cluster 1, location 1135 - 37695:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-7880

PKS_AT (400..713): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 65.5
Malonyl-CoA: 64.7
Methoxymalonyl-CoA: 64.3
Ethylmalonyl-CoA: 47.0
Isobutyryl-CoA: 43.3
Benzoyl-CoA: 27.5
Propionyl-CoA: 23.5
inactive: 20.7
2-Methylbutyryl-CoA: 19.6
trans-1,2-CPDA: 17.4
fatty_acid: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

NODE_13_length_1066851_cov_42.619387 - Region 2 - T1PKS

Download region GenBank file

Location: 225,893 - 273,023 nt. (total: 47,131 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NODE_13_length_1066851_cov_42.619387 - Region 3 - NRPS

Download region GenBank file

Location: 807,950 - 915,464 nt. (total: 107,515 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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Predicted core structure(s)

For candidate cluster 3, location 807949 - 915464:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (iva - pro - iva - iva - pro - iva - iva - pro - X - iva - X - X - iva - iva - X - iva - iva - iva - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-8151

Search NORINE for peptide: strict or relaxed

AMP-binding (695..1097): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1788..2178): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dvlfcglick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2871..3273): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3962..4363): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5058..5449): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dvlfcglick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6147..6549): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgylagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7241..7643): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (8332..8722): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dvlfcglick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (9410..9813): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlgliagvlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (10508..10910): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgfltgvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (11612..12009): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsmmvaifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (12699..13098): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvgmiggiyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (13788..14192): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (14887..15289): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (15980..16379): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsmmvaifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (17065..17467): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (18157..18558): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (19251..19654): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (20349..20753): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvgmvggiyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (21442..21837): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsemvaifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_14_length_1005724_cov_42.454487 - Region 1 - T1PKS,T3PKS

Download region GenBank file

Location: 273,508 - 323,215 nt. (total: 49,708 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 273507 - 323215:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 273507 - 314415:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 275021 - 323215:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-8305

PKS_AT (555..808): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 61.7
Methoxymalonyl-CoA: 54.0
Ethylmalonyl-CoA: 41.0
Propionyl-CoA: 40.1
Malonyl-CoA: 33.5
fatty_acid: 30.9
2-Methylbutyryl-CoA: 26.6
Benzoyl-CoA: 26.4
Isobutyryl-CoA: 24.4
trans-1,2-CPDA: 20.2
CHC-CoA: 20.0
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

NODE_15_length_941171_cov_42.844257 - Region 1 - T1PKS

Download region GenBank file

Location: 186,383 - 233,042 nt. (total: 46,660 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 186382 - 233042:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-8634

PKS_AT (394..711): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 97.9
Methoxymalonyl-CoA: 97.3
Malonyl-CoA: 89.2
Isobutyryl-CoA: 54.2
Propionyl-CoA: 51.7
2-Methylbutyryl-CoA: 49.6
trans-1,2-CPDA: 37.0
inactive: 25.5
fatty_acid: 19.5
Benzoyl-CoA: 18.2
CHC-CoA: 14.9
Acetyl-CoA: 12.5
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -1.6

NODE_15_length_941171_cov_42.844257 - Region 2 - NRPS

Download region GenBank file

Location: 273,382 - 335,316 nt. (total: 61,935 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 273381 - 335316:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (iva - gln - X - iva - X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-8661

Search NORINE for peptide: strict or relaxed

AMP-binding (689..1087): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dmgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1780..2174): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: dggmiggnyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2862..3264): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: daplagcvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3954..4353): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5049..5427): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: shllcsafck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6129..6531): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmgimgvvik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7220..7618): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: daflvgaiak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_15_length_941171_cov_42.844257 - Region 3 - NRPS,T1PKS

Download region GenBank file

Location: 596,798 - 720,108 nt. (total: 123,311 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 596797 - 720108:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (iva - X - iva - iva - iva - gln) + (redmal) + (pro - iva - iva - X - iva - iva - X - iva)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 596797 - 664924:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal) + (iva - X - iva - iva - iva - gln)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 630354 - 678248:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (iva - X - iva - iva - iva - gln) + (redmal) + (pro - iva - iva - X - iva - iva - X - iva)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 6, location 661204 - 720108:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro - iva - iva - X - iva - iva - X - iva)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-8763

Search NORINE for peptide: strict or relaxed

AMP-binding (26..429): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagcfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1122..1519): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsllvavfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2205..2609): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgylagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3294..3696): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgylagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4381..4779): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dvgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5467..5863): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: dgsmlgavdk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-8769

Search NORINE for peptide: strict or relaxed

AMP-binding (12..160): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: di--vggvak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-8770

PKS_AT (543..863): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 56.4
Methylmalonyl-CoA: 55.7
Methoxymalonyl-CoA: 48.2
fatty_acid: 38.8
Ethylmalonyl-CoA: 28.5
Isobutyryl-CoA: 23.6
inactive: 19.9
Propionyl-CoA: 19.0
Benzoyl-CoA: 12.7
trans-1,2-CPDA: 12.6
Acetyl-CoA: 10.7
2-Methylbutyryl-CoA: 9.4
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ETHZIMBMK001_gene-8774

Search NORINE for peptide: strict or relaxed

AMP-binding (877..1270): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dilfcgitck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1960..2361): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgylagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3053..3456): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4148..4543): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvslivavfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5232..5631): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflaavfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6318..6721): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7407..7801): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvslivavfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (8487..8890): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_15_length_941171_cov_42.844257 - Region 4 - NRPS

Download region GenBank file

Location: 822,101 - 890,124 nt. (total: 68,024 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 7, location 822100 - 890124:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala - X - D-X - X - D-val - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-8819

Search NORINE for peptide: strict or relaxed

AMP-binding (248..642): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dvfciltilk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1724..2119): X

NRPSPredictor2: phe, trp, phg, tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dgascvgick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2795..3190): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: daifmggifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4343..4738): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dpahvggiak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5425..5816): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: dlafvggvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6890..7284): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvgyagviwk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7965..8364): X

NRPSPredictor2: phe, trp, phg, tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dgvmvvgvck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_19_length_791210_cov_42.638320 - Region 1 - NRPS-like,T1PKS

Download region GenBank file

Location: 46,338 - 93,909 nt. (total: 47,572 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 46337 - 93909:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-9781

Search NORINE for peptide: strict or relaxed

AMP-binding (37..431): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: dmlqlglvyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

PKS_AT (1174..1475): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 159.5
inactive: 103.9
Methoxymalonyl-CoA: 64.9
Methylmalonyl-CoA: 64.6
Propionyl-CoA: 42.2
Ethylmalonyl-CoA: 38.2
trans-1,2-CPDA: 31.6
Benzoyl-CoA: 27.9
Isobutyryl-CoA: 23.6
2-Methylbutyryl-CoA: 19.0
Acetyl-CoA: 17.7
CHC-CoA: 14.9
fatty_acid: 12.9
3-Methylbutyryl-CoA: 0.0

NODE_20_length_754805_cov_42.550344 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 656,674 - 709,141 nt. (total: 52,468 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 656673 - 709141:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-10250

Search NORINE for peptide: strict or relaxed

PKS_AT (419..733): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 77.0
Methoxymalonyl-CoA: 64.2
Ethylmalonyl-CoA: 53.5
Malonyl-CoA: 43.8
Isobutyryl-CoA: 37.5
fatty_acid: 34.5
Benzoyl-CoA: 33.6
trans-1,2-CPDA: 33.4
Propionyl-CoA: 27.9
2-Methylbutyryl-CoA: 24.4
CHC-CoA: 12.1
3-Methylbutyryl-CoA: 11.2
Acetyl-CoA: 8.9
inactive: 0.0

AMP-binding (2914..3327): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: nhdkfgsisk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_22_length_697479_cov_42.070416 - Region 1 - NRPS

Download region GenBank file

Location: 356,440 - 400,894 nt. (total: 44,455 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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NRPS/PKS domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 356439 - 400894:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-10612

Search NORINE for peptide: strict or relaxed

AMP-binding (483..894): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: nhdkfgsisk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_26_length_643428_cov_41.885604 - Region 1 - terpene

Download region GenBank file

Location: 590,414 - 611,472 nt. (total: 21,059 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NODE_30_length_574181_cov_42.457501 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 2,746 - 69,115 nt. (total: 66,370 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

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Predicted core structure(s)

For candidate cluster 1, location 2745 - 69115:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 2745 - 48310:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 23668 - 69115:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-12304

Search NORINE for peptide: strict or relaxed

AMP-binding (220..629): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dvlhhvanek
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-12312

PKS_AT (327..644): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 61.8
Methoxymalonyl-CoA: 53.6
Propionyl-CoA: 31.2
Malonyl-CoA: 22.5
CHC-CoA: 14.9
fatty_acid: 14.7
Ethylmalonyl-CoA: 14.4
Benzoyl-CoA: 12.4
trans-1,2-CPDA: 11.3
2-Methylbutyryl-CoA: 11.2
Isobutyryl-CoA: 9.5
3-Methylbutyryl-CoA: 5.6
Acetyl-CoA: 2.0
inactive: 0.0

NODE_31_length_548174_cov_42.595227 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 427,869 - 480,568 nt. (total: 52,700 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 427868 - 480568:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-12656

PKS_AT (559..875): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 77.2
Methoxymalonyl-CoA: 67.1
Ethylmalonyl-CoA: 41.2
Propionyl-CoA: 33.5
Benzoyl-CoA: 32.1
Isobutyryl-CoA: 28.3
fatty_acid: 19.6
Malonyl-CoA: 17.5
CHC-CoA: 16.1
2-Methylbutyryl-CoA: 13.0
trans-1,2-CPDA: 10.4
Acetyl-CoA: 5.5
inactive: 0.0
3-Methylbutyryl-CoA: 0.0

ETHZIMBMK001_gene-12657

Search NORINE for peptide: strict or relaxed

AMP-binding (111..526): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmsvfghfak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_33_length_436582_cov_42.267914 - Region 1 - terpene

Download region GenBank file

Location: 46,231 - 67,421 nt. (total: 21,191 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NODE_34_length_366628_cov_43.004755 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 195,159 - 247,224 nt. (total: 52,066 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

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Predicted core structure(s)

For candidate cluster 1, location 195158 - 247224:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-13086

Search NORINE for peptide: strict or relaxed

PKS_AT (553..866): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.8
Methoxymalonyl-CoA: 77.7
Ethylmalonyl-CoA: 62.8
Malonyl-CoA: 52.4
Benzoyl-CoA: 43.2
Isobutyryl-CoA: 37.9
trans-1,2-CPDA: 36.0
Propionyl-CoA: 30.4
3-Methylbutyryl-CoA: 23.4
fatty_acid: 22.2
CHC-CoA: 13.8
Acetyl-CoA: 11.7
inactive: 0.0
2-Methylbutyryl-CoA: -1.6

AMP-binding (2541..2946): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dltylavcgk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_34_length_366628_cov_43.004755 - Region 2 - NRPS-like

Download region GenBank file

Location: 283,415 - 326,528 nt. (total: 43,114 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 283414 - 326528:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-13115

Search NORINE for peptide: strict or relaxed

AMP-binding (20..337): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: --plvgtclk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_38_length_300474_cov_42.105034 - Region 1 - T1PKS

Download region GenBank file

Location: 31,353 - 78,889 nt. (total: 47,537 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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Predicted core structure(s)

For candidate cluster 1, location 31352 - 78889:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-13491

PKS_AT (586..913): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Propionyl-CoA: 62.5%; 2-Methylbutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 79.8
Methoxymalonyl-CoA: 66.7
Propionyl-CoA: 47.9
Ethylmalonyl-CoA: 45.7
Isobutyryl-CoA: 38.6
Malonyl-CoA: 35.1
fatty_acid: 28.4
2-Methylbutyryl-CoA: 23.2
CHC-CoA: 23.0
trans-1,2-CPDA: 19.3
inactive: 13.7
Benzoyl-CoA: 11.5
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

NODE_40_length_293996_cov_42.939711 - Region 1 - T1PKS

Download region GenBank file

Location: 2,889 - 47,226 nt. (total: 44,338 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

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NODE_40_length_293996_cov_42.939711 - Region 2 - NRPS

Download region GenBank file

Location: 79,867 - 126,898 nt. (total: 47,032 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

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Predicted core structure(s)

For candidate cluster 2, location 79866 - 126898:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-13724

Search NORINE for peptide: strict or relaxed

AMP-binding (220..627): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: saclvggftk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1315..1716): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvafigciyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-13725

PKS_AT (1..256): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 68.0
Methylmalonyl-CoA: 65.2
Methoxymalonyl-CoA: 59.8
Ethylmalonyl-CoA: 42.1
Propionyl-CoA: 27.7
Isobutyryl-CoA: 23.2
2-Methylbutyryl-CoA: 22.7
fatty_acid: 17.9
inactive: 15.6
Benzoyl-CoA: 14.8
trans-1,2-CPDA: 9.1
CHC-CoA: 8.4
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

NODE_40_length_293996_cov_42.939711 - Region 3 - T1PKS

Download region GenBank file

Location: 166,909 - 215,968 nt. (total: 49,060 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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Predicted core structure(s)

For candidate cluster 3, location 166908 - 215968:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-13752

PKS_AT (547..865): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 68.6
Methoxymalonyl-CoA: 60.8
Ethylmalonyl-CoA: 46.6
Malonyl-CoA: 23.4
Propionyl-CoA: 22.3
Benzoyl-CoA: 20.8
Isobutyryl-CoA: 19.6
fatty_acid: 15.6
2-Methylbutyryl-CoA: 13.9
inactive: 13.6
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

NODE_44_length_206991_cov_41.867573 - Region 1 - T1PKS

Download region GenBank file

Location: 34,633 - 82,338 nt. (total: 47,706 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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Predicted core structure(s)

For candidate cluster 1, location 34632 - 82338:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14059

PKS_AT (874..1168): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 46.2
inactive: 42.1
Methoxymalonyl-CoA: 39.3
Methylmalonyl-CoA: 30.5
Propionyl-CoA: 23.6
CHC-CoA: 22.1
Ethylmalonyl-CoA: 21.4
2-Methylbutyryl-CoA: 19.5
Benzoyl-CoA: 17.8
Acetyl-CoA: 16.3
trans-1,2-CPDA: 13.5
Isobutyryl-CoA: 13.2
fatty_acid: 12.9
3-Methylbutyryl-CoA: 10.2

NODE_46_length_192017_cov_42.184917 - Region 1 - terpene

Download region GenBank file

Location: 50,941 - 73,308 nt. (total: 22,368 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NODE_48_length_126658_cov_42.504625 - Region 1 - NRPS,T1PKS

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Location: 1 - 85,434 nt. (total: 85,434 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 85434:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - val - ile - X - X - X - X - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 74283:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - val - ile - X - X - X - X - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 38027 - 85434:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - val - ile - X - X - X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14302

Search NORINE for peptide: strict or relaxed

AMP-binding (334..732): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmciiaipik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1408..1811): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: dawmyggtfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2903..3308): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: dgwfigavfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4398..4803): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawlygvvsk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5896..6299): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvwiyaavik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (7391..7793): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawffggcyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (8878..9275): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dihniaaisk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (9954..10359): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmwilggfak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-14303

PKS_AT (561..856): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; 2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 61.4
Malonyl-CoA: 54.6
Methoxymalonyl-CoA: 46.5
inactive: 25.2
Propionyl-CoA: 24.5
Isobutyryl-CoA: 23.6
trans-1,2-CPDA: 15.3
fatty_acid: 13.6
Benzoyl-CoA: 9.2
Acetyl-CoA: 8.6
Ethylmalonyl-CoA: 0.7
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

NODE_49_length_115311_cov_42.194838 - Region 1 - NRPS-like

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Location: 19,790 - 62,639 nt. (total: 42,850 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

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NODE_52_length_101685_cov_42.543993 - Region 1 - T1PKS

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Location: 40,673 - 88,526 nt. (total: 47,854 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 40672 - 88526:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14462

PKS_AT (578..902): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 88.4
Methoxymalonyl-CoA: 68.1
Malonyl-CoA: 59.3
Isobutyryl-CoA: 59.0
Propionyl-CoA: 52.9
Ethylmalonyl-CoA: 51.5
trans-1,2-CPDA: 35.3
2-Methylbutyryl-CoA: 32.7
Benzoyl-CoA: 31.1
3-Methylbutyryl-CoA: 25.5
CHC-CoA: 24.7
fatty_acid: 24.6
Acetyl-CoA: 12.3
inactive: 0.0

NODE_53_length_97316_cov_42.115900 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 4,882 - 56,785 nt. (total: 51,904 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4881 - 56785:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14485

Search NORINE for peptide: strict or relaxed

PKS_AT (587..898): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 86.7
Methylmalonyl-CoA: 85.3
Malonyl-CoA: 76.3
Isobutyryl-CoA: 70.4
Ethylmalonyl-CoA: 40.1
Benzoyl-CoA: 39.4
3-Methylbutyryl-CoA: 37.4
Propionyl-CoA: 37.2
2-Methylbutyryl-CoA: 28.2
inactive: 27.2
trans-1,2-CPDA: 23.7
Acetyl-CoA: 20.6
fatty_acid: 13.8
CHC-CoA: 13.1

AMP-binding (2885..3291): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvayiaevqk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_58_length_55987_cov_40.959900 - Region 1 - T1PKS

Download region GenBank file

Location: 13,977 - 55,987 nt. (total: 42,011 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13976 - 55987:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14596

PKS_AT (489..786): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 100.5
inactive: 64.9
Methylmalonyl-CoA: 54.9
Methoxymalonyl-CoA: 45.3
Propionyl-CoA: 41.3
2-Methylbutyryl-CoA: 26.1
Benzoyl-CoA: 24.1
Ethylmalonyl-CoA: 22.7
CHC-CoA: 22.0
Isobutyryl-CoA: 21.6
fatty_acid: 13.2
trans-1,2-CPDA: 9.9
3-Methylbutyryl-CoA: 6.7
Acetyl-CoA: 0.0

NODE_75_length_37189_cov_41.313699 - Region 1 - NRPS

Download region GenBank file

Location: 1 - 37,189 nt. (total: 37,189 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 37189:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro - X - X - iva - X - iva)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14807

Search NORINE for peptide: strict or relaxed

AMP-binding (872..1259): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dmlscaitck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1951..2349): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvamvcgvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3033..3413): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dgvllgvimk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4111..4514): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dvgflagvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5211..5613): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlgflagcfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (6312..6714): iva

NRPSPredictor2: iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: iva

Stachelhaus prediction details:

Stachelhaus sequence:: dlgfltgvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

NODE_85_length_32612_cov_41.031351 - Region 1 - T1PKS

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Location: 1 - 30,341 nt. (total: 30,341 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NODE_92_length_29195_cov_40.099869 - Region 1 - T1PKS

Download region GenBank file

Location: 1 - 29,195 nt. (total: 29,195 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 29195:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ETHZIMBMK001_gene-14962

Search NORINE for peptide: strict or relaxed

AMP-binding (75..397): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---ifgavsk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ETHZIMBMK001_gene-14963

PKS_AT (583..895): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Ethylmalonyl-CoA: 62.5%; Methylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 75.6
Methoxymalonyl-CoA: 63.5
Malonyl-CoA: 55.5
Propionyl-CoA: 42.7
Ethylmalonyl-CoA: 40.8
Isobutyryl-CoA: 31.5
fatty_acid: 23.8
CHC-CoA: 17.0
Benzoyl-CoA: 13.1
Acetyl-CoA: 12.6
inactive: 10.4
2-Methylbutyryl-CoA: 9.8
3-Methylbutyryl-CoA: 8.9
trans-1,2-CPDA: 6.8

NODE_95_length_26577_cov_43.470302 - Region 1 - NRPS-like

Download region GenBank file

Location: 1 - 26,577 nt. (total: 26,577 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

NODE_113_length_19231_cov_41.530229 - Region 1 - T1PKS

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Location: 1 - 19,231 nt. (total: 19,231 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

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NODE_164_length_9054_cov_53.570235 - Region 1 - terpene

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Location: 1 - 9,054 nt. (total: 9,054 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NODE_281_length_2750_cov_54.194164 - Region 1 - terpene

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Location: 1 - 2,750 nt. (total: 2,750 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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